Commerce fell to George Walton 24-14 on Friday in Monroe.
Turnovers continued to impact the Tigers, who gave up 24 unanswered points after taking a 7-0 lead to open the first quarter.
Commerce (3-6, 2-3) faces a must-win situation next week versus Social Circle to lock up the No. 4 playoff spot in Region 8-A.
The Bulldogs (7-2, 4-1) secured home field advantage in the first round of the state playoffs as the region’s No. 2 seed. Undefeated Prince Avenue claimed the No. 1 seed after its win over Athens Christian. It’s the Wolverines’ first region championship in school history.